COGNITIVE-AFFECTIVE SYNDROME IN CHIARI TYPE I MALFORMATION: NEUROPSYCHOLOGICAL ANALYSIS OF THREE CLINICAL CASES
Abstract
Chiari malformation type I (CM-I) is a congenital neurological condition that can significantly impact patients’ quality of life. Several studies have reported cognitive and emotional dysfunctions in individuals with CM-I, highlighting the need for a deeper understanding of its symptomatology. The aim of this study was to assess executive functioning and trait anxiety in three adult patients diagnosed with CM-I. A case study design was employed using a mixed-methods approach. Participants were three adult women aged between 28 and 55 years. The results revealed variability in cognitive profiles, showing that patients with low executive performance reported active physical symptoms that interfered with daily functioning, while the patient with higher executive functioning was clinically asymptomatic. Emotionally, all three cases exhibited elevated trait anxiety scores. These findings underscore the importance of a comprehensive assessment of CM-I that includes not only physical symptoms but also cognitive and emotional factors, in order to guide more holistic and personalized interventions.
Keywords: Chiari Malformation Type I; cerebellum; executive functions; anxiety; neuropsychological assessment.
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Copyright (c) 2026 Angie Paola Herrera Morales , Vanesa Perez
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